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Fletta eftir efnisorði "Disease Progression"

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BRN2 is a non-canonical melanoma tumor-suppressor

Hamm, Michael; Sohier, Pierre; Petit, Valérie; Raymond, Jérémy H.; Delmas, Véronique; Le Coz, Madeleine; Gesbert, Franck; Kenny, Colin; Aktary, Zackie; Pouteaux, Marie; Rambow, Florian; Sarasin, Alain; Charoenchon, Nisamanee; Bellacosa, Alfonso; Sanchez-del-Campo, Luis; Mosteo, Laura; Lauss, Martin; Meijer, Dies; Steingrímsson, Eiríkur; Jönsson, Göran B.; Cornell, Robert A.; Davidson, Irwin; Goding, Colin R.; Larue, Lionel (2021-06-17)

While the major drivers of melanoma initiation, including activation of NRAS/BRAF and loss of PTEN or CDKN2A, have been identified, the role of key transcription factors that impose altered transcriptional states in response to deregulated signaling ...
Cerebrospinal Fluid C18 Ceramide Associates with Markers of Alzheimer's Disease and Inflammation at the Pre- And Early Stages of Dementia

Teitsdóttir, Unnur Diljá; Halldórsson, Skarphéðinn; Rolfsson, Óttar; Lund, Sigrún H.; Jónsdóttir, María Kristín; Snædal, Jón G.; Petersen, Pétur Henry (2021-05-04)

BACKGROUND: Understanding how dysregulation in lipid metabolism relates to the severity of Alzheimer's disease (AD) pathology might be critical in developing effective treatments. OBJECTIVE: To identify lipid species in cerebrospinal fluid (CSF) ...
The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large-Scale Proteomics Scan in Iceland : A Large-Scale Proteomics Scan in Iceland

Styrkarsdottir, Unnur; Lund, S.H.; Saevarsdottir, S.; Magnusson, M.I.; Gunnarsdottir, K.; Norddahl, Gudmundur L.; Frigge, Michael L.; Ivarsdottir, E.V.; Bjornsdottir, Gyda; Holm, Hilma; Thorgeirsson, Guðmundur; Rafnar, T.; Jonsdottir, I.; Ingvarsson, T.; Jonsson, H.; Sulem, P.; Thorsteinsdottir, U.; Gudbjartsson, Daniel Fannar; Stefansson, K.; Thorgeirsson, Gudmundur; Ingvarsson, Þorvaldur (2021-11)

Objective: Biomarkers for diagnosis and progression of osteoarthritis (OA) are lacking. This study was undertaken to identify circulating biomarkers for OA that could predict disease occurrence and/or progression to joint replacement. Methods: Using ...
Detection and Early Referral of Patients With Interstitial Lung Abnormalities : An Expert Survey Initiative

ILA Study Group (2022-02-01)

Background: Interstitial lung abnormalities (ILA) may represent undiagnosed early-stage or subclinical interstitial lung disease (ILD). ILA are often observed incidentally in patients who subsequently develop clinically overt ILD. There is limited ...
Retinal oxygen saturation changes progressively over time in diabetic retinopathy

Harðarson, Sveinn Hákon; Stefánsson, Einar; Bek, Toke (2021-05-12)

Purpose According to cross-sectional studies, oxygen saturation is elevated in retinal vessels in diabetic patients. We evaluated how retinal oxygenation (metabolic marker), vessel diameters and retinopathy grade (structural markers) change over time ...
Validation of the adjusted multi-biomarker disease activity score as a prognostic test for radiographic progression in rheumatoid arthritis : a combined analysis of multiple studies

Curtis, Jeffrey R.; Weinblatt, Michael E.; Shadick, Nancy A.; Brahe, Cecilie H.; Østergaard, Mikkel; Hetland, Merete Lund; Sævarsdóttir, Sædís; Horton, Megan; Mabey, Brent; Flake, Darl D.; Ben-Shachar, Rotem; Sasso, Eric H.; Huizinga, T. W. (2021-01-04)

BACKGROUND: The multi-biomarker disease activity (MBDA) test measures 12 serum protein biomarkers to quantify disease activity in RA patients. A newer version of the MBDA score, adjusted for age, sex, and adiposity, has been validated in two cohorts ...

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Fletta eftir efnisorði "Disease Progression"

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